| BRU–MAD | Zaventem – Madrid | 349 |
| BCN–BRU | Barcelona – Zaventem | 287 |
| AGP–BRU | Málaga – Zaventem | 285 |
| BRU–LIS | Zaventem – Lisbon | 245 |
| ALC–BRU | Alicante – Zaventem | 233 |
| BRU–CPH | Zaventem – Copenhagen | 182 |
| BRU–FCO | Zaventem – Rome | 181 |
| ATH–BRU | Spata-Artemida – Zaventem | 174 |
| BRU–TFS | Zaventem – Tenerife | 136 |
| ARN–BRU | Stockholm – Zaventem | 136 |
| BRU–WAW | Zaventem – Warsaw | 122 |
| BRU–OSL | Zaventem – Oslo (Gardermoen) | 117 |
| BRU–OPO | Zaventem – Porto | 116 |
| BRU–HER | Zaventem – Heraklion | 107 |
| BRU–FAO | Zaventem – Faro | 104 |
| BRU–LHR | Zaventem – London | 102 |
| BRU–IAD | Zaventem – Dulles | 89 |
| BRU–LIN | Zaventem – Segrate (MI) | 86 |
| BRU–IBZ | Zaventem – Ibiza (Eivissa) | 84 |
| BRU–VIE | Zaventem – Vienna | 84 |
| BRU–PMI | Zaventem – Palma de Mallorca | 83 |
| BRU–LPA | Zaventem – Gran Canaria Island | 70 |
| BRU–VLC | Zaventem – Valencia | 65 |
| BRU–RHO | Zaventem – Rhodes | 62 |
| BRU–HRG | Zaventem – Hurghada | 62 |
| BRU–JFK | Zaventem – New York | 60 |
| BRU–DSS | Zaventem – Dakar | 58 |
| BRU–KGS | Zaventem – Kos Island | 55 |
| ABJ–OUA | Abidjan – Ouagadougou | 54 |
| ACC–BRU | Accra – Zaventem | 50 |
| BRU–FIH | Zaventem – Kinshasa | 41 |
| BRU–NCE | Zaventem – Nice, Alpes-Maritimes | 41 |
| BRU–GOT | Zaventem – Göteborg | 40 |
| BRU–NBO | Zaventem – Nairobi | 37 |
| BRU–CHQ | Zaventem – Souda | 34 |
| BRU–BUD | Zaventem – Budapest | 34 |
| BRU–MXP | Zaventem – Ferno (VA) | 34 |
| BRU–NAP | Zaventem – Napoli | 32 |
| BIO–BRU | Bilbao – Zaventem | 32 |
| BRU–EVN | Zaventem – Yerevan | 32 |
| BRU–GVA | Zaventem – Geneva | 32 |
| BRU–CTA | Zaventem – Catania | 30 |
| BRU–MIR | Zaventem – Monastir | 30 |
| BRU–TLS | Zaventem – Toulouse/Blagnac | 30 |
| BER–BRU | Berlin – Zaventem | 29 |
| BRU–MRS | Zaventem – Marignane, Bouches-du-Rhône | 28 |
| BRU–EDI | Zaventem – Ingliston, Edinburgh | 27 |
| BRU–ZTH | Zaventem – Zakynthos | 26 |
| BRU–DJE | Zaventem – Mellita | 25 |
| BRU–PRG | Zaventem – Prague | 24 |
| BRU–FLR | Zaventem – Firenze (FI) | 24 |
| BRU–DLA | Zaventem – Douala | 24 |
| BRU–KGL | Zaventem – Kigali | 23 |
| BRU–ZRH | Zaventem – Zurich | 23 |
| ACE–BRU | San Bartolomé – Zaventem | 22 |
| BRU–NSI | Zaventem – Yaoundé | 22 |
| BRU–CFU | Zaventem – Kerkyra (Corfu) | 22 |
| BRU–OUA | Zaventem – Ouagadougou | 22 |
| BRU–VNO | Zaventem – Vilnius | 22 |
| BRU–TLV | Zaventem – Tel Aviv | 22 |
| BRU–MUC | Zaventem – Munich | 22 |
| BRU–FNA | Zaventem – Freetown (Lungi-Town) | 21 |
| AHU–BRU | Al Hoceima – Zaventem | 20 |
| BRU–RMF | Zaventem – Marsa Alam | 20 |
| BGO–BRU | Bergen – Zaventem | 19 |
| BRU–VCE | Zaventem – Venezia (VE) | 19 |
| BRU–HAM | Zaventem – Hamburg | 17 |
| BRU–FNC | Zaventem – Funchal | 17 |
| BRU–EBB | Zaventem – Entebbe | 17 |
| BRU–CDG | Zaventem – Paris (Roissy-en-France, Val-d'Oise) | 15 |
| ABJ–BRU | Abidjan – Zaventem | 15 |
| BRU–ROB | Zaventem – Monrovia | 14 |
| BRU–MAN | Zaventem – Manchester, Greater Manchester | 13 |
| BRU–LYS | Zaventem – Colombier-Saugnieu, Rhône | 13 |
| BLQ–BRU | Bologna – Zaventem | 12 |
| BRU–COO | Zaventem – Cotonou | 11 |
| BRU–KRK | Zaventem – Balice | 11 |
| BRU–SMI | Zaventem – Samos Island | 11 |
| BRU–JRO | Zaventem – Arusha | 9 |
| BRU–CKY | Zaventem – Conakry | 9 |
| BRU–FUE | Zaventem – El Matorral | 9 |
| BJM–BRU | Bujumbura – Zaventem | 7 |
| BRU–MJT | Zaventem – Mytilene | 7 |
| BRU–OLB | Zaventem – Olbia (SS) | 7 |
| BRU–PMO | Zaventem – Palermo | 6 |
| BJL–BRU | Banjul (Yundum) – Zaventem | 5 |
| BRU–LJU | Zaventem – Zgornji Brnik | 3 |
| EBB–KGL | Entebbe – Kigali | 3 |
| BRU–FRA | Zaventem – Frankfurt am Main | 3 |
| BRU–DBV | Zaventem – Dubrovnik | 3 |
| FNA–ROB | Freetown (Lungi-Town) – Monrovia | 3 |
| BRU–SPU | Zaventem – Split | 3 |
| BOO–BRUonce | Bodø – Zaventem | 1 |
| BRU–XCRonce | Zaventem – Chalons en Champagne | 1 |
| BRU–CIAonce | Zaventem – Rome | 1 |
| BRU–ZADonce | Zaventem – Zadar | 1 |
.jpg){kind=link}