| HAV–MIA | Havana – Miami | 330 |
| MIA–SDQ | Miami – Santo Domingo | 289 |
| DEL–HKG | New Delhi – Hong Kong | 278 |
| CVG–LEJ | Cincinnati / Covington – Schkeuditz | 169 |
| DXB–PVG | Dubai – Shanghai (Pudong) | 107 |
| BRU–CVG | Zaventem – Cincinnati / Covington | 101 |
| BFS–EMA | Belfast – Nottingham, Leicestershire | 98 |
| DWC–PVG | Dubai(Jebel Ali) – Shanghai (Pudong) | 92 |
| HKG–MXP | Hong Kong – Ferno (VA) | 91 |
| CVG–EMA | Cincinnati / Covington – Nottingham, Leicestershire | 76 |
| EMA–LEJ | Nottingham, Leicestershire – Schkeuditz | 75 |
| MIA–SNU | Miami – Santa Clara | 71 |
| HKG–LEJ | Hong Kong – Schkeuditz | 69 |
| BRU–PVG | Zaventem – Shanghai (Pudong) | 66 |
| LEJ–PVG | Schkeuditz – Shanghai (Pudong) | 58 |
| HOG–MIA | Holguin – Miami | 56 |
| BRU–HKG | Zaventem – Hong Kong | 54 |
| JFK–LEJ | New York – Schkeuditz | 47 |
| BAH–PVG | Manama – Shanghai (Pudong) | 46 |
| CVG–HKG | Cincinnati / Covington – Hong Kong | 44 |
| CGN–EMA | Köln (Cologne) – Nottingham, Leicestershire | 41 |
| HAV–PUJ | Havana – Punta Cana | 37 |
| CPH–EMA | Copenhagen – Nottingham, Leicestershire | 32 |
| BAH–CVG | Manama – Cincinnati / Covington | 30 |
| BAH–HKG | Manama – Hong Kong | 30 |
| EMA–MXP | Nottingham, Leicestershire – Ferno (VA) | 30 |
| EMA–JFK | Nottingham, Leicestershire – New York | 30 |
| EDI–MXP | Ingliston, Edinburgh – Ferno (VA) | 29 |
| BAH–LEJ | Manama – Schkeuditz | 28 |
| BRU–EMA | Zaventem – Nottingham, Leicestershire | 28 |
| LAX–NGO | Los Angeles – Tokoname | 28 |
| BRU–DWC | Zaventem – Dubai(Jebel Ali) | 27 |
| GEO–SDQ | Georgetown – Santo Domingo | 27 |
| EDI–LEJ | Ingliston, Edinburgh – Schkeuditz | 27 |
| EMA–KEF | Nottingham, Leicestershire – Reykjavík | 25 |
| FDF–SDQ | Fort-de-France – Santo Domingo | 22 |
| HAV–SDQ | Havana – Santo Domingo | 22 |
| PTP–SDQ | Pointe-à-Pitre – Santo Domingo | 20 |
| CVG–MXP | Cincinnati / Covington – Ferno (VA) | 20 |
| ABZ–EMA | Aberdeen – Nottingham, Leicestershire | 19 |
| DEL–LEJ | New Delhi – Schkeuditz | 17 |
| PBM–SDQ | Paramaribo – Santo Domingo | 15 |
| DWC–LEJ | Dubai(Jebel Ali) – Schkeuditz | 14 |
| BKK–DWC | Bangkok – Dubai(Jebel Ali) | 14 |
| GVA–LEJ | Geneva – Schkeuditz | 12 |
| DEL–EMA | New Delhi – Nottingham, Leicestershire | 11 |
| ANU–SDQ | Osbourn – Santo Domingo | 11 |
| EMA–LAX | Nottingham, Leicestershire – Los Angeles | 10 |
| BSL–LEJ | Bâle / Mulhouse – Schkeuditz | 10 |
| BLQ–EMA | Bologna – Nottingham, Leicestershire | 9 |
| CVG–PVG | Cincinnati / Covington – Shanghai (Pudong) | 8 |
| BAH–EMA | Manama – Nottingham, Leicestershire | 8 |
| AXA–SDQ | The Valley – Santo Domingo | 8 |
| DWC–WUX | Dubai(Jebel Ali) – Wuxi | 7 |
| BUD–EMA | Budapest – Nottingham, Leicestershire | 7 |
| BSL–EMA | Bâle / Mulhouse – Nottingham, Leicestershire | 7 |
| DXB–EMA | Dubai – Nottingham, Leicestershire | 7 |
| BRU–BSL | Zaventem – Bâle / Mulhouse | 7 |
| BAH–BRU | Manama – Zaventem | 5 |
| EMA–HKG | Nottingham, Leicestershire – Hong Kong | 5 |
| SDQ–STT | Santo Domingo – Charlotte Amalie | 5 |
| SCU–SDQ | Santiago – Santo Domingo | 5 |
| EMA–MAN | Nottingham, Leicestershire – Manchester, Greater Manchester | 4 |
| DWC–EMA | Dubai(Jebel Ali) – Nottingham, Leicestershire | 3 |
| BON–SDQ | Kralendijk – Santo Domingo | 3 |
| SDQ–SKB | Santo Domingo – Basseterre | 2 |
| CGN–OSL | Köln (Cologne) – Oslo (Gardermoen) | 2 |
| CMW–SDQonce | Camaguey – Santo Domingo | 1 |
| HOG–SDQonce | Holguin – Santo Domingo | 1 |
| BLQ–GVAonce | Bologna – Geneva | 1 |
| HAV–XPLonce | Havana – Palmerola | 1 |
| SDQ–UVFonce | Santo Domingo – Vieux Fort | 1 |
| CVG–MZJonce | Cincinnati / Covington – MZJ | 1 |
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