| GVA–LHR | Geneva – London | 325 |
| PMI–ZRH | Palma de Mallorca – Zurich | 288 |
| GVA–OPO | Geneva – Porto | 276 |
| MAD–ZRH | Madrid – Zurich | 273 |
| AYT–ZRH | Antalya – Zurich | 273 |
| LIS–ZRH | Lisbon – Zurich | 266 |
| GVA–LIS | Geneva – Lisbon | 252 |
| LHR–ZRH | London – Zurich | 218 |
| ATH–ZRH | Spata-Artemida – Zurich | 215 |
| EZE–GRU | Buenos Aires (Ezeiza) – São Paulo | 186 |
| CPH–ZRH | Copenhagen – Zurich | 184 |
| ORD–ZRH | Chicago – Zurich | 165 |
| JFK–ZRH | New York – Zurich | 165 |
| OPO–ZRH | Porto – Zurich | 162 |
| DEL–ZRH | New Delhi – Zurich | 161 |
| TLV–ZRH | Tel Aviv – Zurich | 159 |
| AGP–ZRH | Málaga – Zurich | 149 |
| BCN–ZRH | Barcelona – Zurich | 144 |
| LCA–ZRH | Larnaca – Zurich | 128 |
| HKG–ZRH | Hong Kong – Zurich | 126 |
| SIN–ZRH | Singapore – Zurich | 124 |
| BKK–ZRH | Bangkok – Zurich | 123 |
| ATH–GVA | Spata-Artemida – Geneva | 121 |
| SFO–ZRH | San Francisco – Zurich | 121 |
| IAD–ZRH | Dulles – Zurich | 112 |
| AGP–GVA | Málaga – Geneva | 109 |
| EWR–ZRH | Newark – Zurich | 107 |
| FCO–ZRH | Rome – Zurich | 106 |
| YYZ–ZRH | Toronto – Zurich | 103 |
| BOS–ZRH | Boston – Zurich | 103 |
| WAW–ZRH | Warsaw – Zurich | 102 |
| MLA–ZRH | Valletta – Zurich | 100 |
| OSL–ZRH | Oslo (Gardermoen) – Zurich | 100 |
| GVA–RAK | Geneva – Marrakesh | 98 |
| BER–ZRH | Berlin – Zurich | 95 |
| DUB–ZRH | Dublin – Zurich | 95 |
| VLC–ZRH | Valencia – Zurich | 92 |
| AMS–ZRH | Amsterdam – Zurich | 92 |
| ARN–ZRH | Stockholm – Zurich | 90 |
| GVA–PMI | Geneva – Palma de Mallorca | 87 |
| BDS–ZRH | Brindisi – Zurich | 86 |
| BEG–ZRH | Belgrade – Zurich | 85 |
| GVA–PRN | Geneva – Prishtina | 84 |
| CDG–ZRH | Paris (Roissy-en-France, Val-d'Oise) – Zurich | 82 |
| PMO–ZRH | Palermo – Zurich | 81 |
| GVA–VLC | Geneva – Valencia | 80 |
| LCY–ZRH | London – Zurich | 74 |
| FAO–GVA | Faro – Geneva | 70 |
| SKG–ZRH | Thessaloniki – Zurich | 69 |
| CAI–ZRH | Cairo – Zurich | 68 |
| PRG–ZRH | Prague – Zurich | 65 |
| OTP–ZRH | Otopeni – Zurich | 64 |
| LGW–ZRH | London – Zurich | 62 |
| NAP–ZRH | Napoli – Zurich | 62 |
| PVG–ZRH | Shanghai (Pudong) – Zurich | 61 |
| ALC–ZRH | Alicante – Zurich | 60 |
| ICN–ZRH | Seoul – Zurich | 59 |
| LAX–ZRH | Los Angeles – Zurich | 59 |
| LJU–ZRH | Zgornji Brnik – Zurich | 59 |
| GRU–ZRH | São Paulo – Zurich | 59 |
| BOM–ZRH | Mumbai – Zurich | 57 |
| MAN–ZRH | Manchester, Greater Manchester – Zurich | 57 |
| AYT–SKP | Antalya – Ilinden | 57 |
| GVA–NCE | Geneva – Nice, Alpes-Maritimes | 56 |
| MIA–ZRH | Miami – Zurich | 55 |
| GVA–JFK | Geneva – New York | 53 |
| JNB–ZRH | Johannesburg – Zurich | 48 |
| AYT–GVA | Antalya – Geneva | 47 |
| MUC–ZRH | Munich – Zurich | 46 |
| NRT–ZRH | Narita – Zurich | 45 |
| BUD–ZRH | Budapest – Zurich | 45 |
| HAM–ZRH | Hamburg – Zurich | 42 |
| GVA–HER | Geneva – Heraklion | 40 |
| YUL–ZRH | Montréal – Zurich | 39 |
| TIA–ZRH | Rinas – Zurich | 38 |
| MXP–ZRH | Ferno (VA) – Zurich | 38 |
| SKP–ZRH | Ilinden – Zurich | 38 |
| FRA–GVA | Frankfurt am Main – Geneva | 36 |
| VNO–ZRH | Vilnius – Zurich | 29 |
| GOT–ZRH | Göteborg – Zurich | 27 |
| TLL–ZRH | Tallinn – Zurich | 27 |
| DBV–ZRH | Dubrovnik – Zurich | 25 |
| SOF–ZRH | Sofia – Zurich | 24 |
| KRK–ZRH | Balice – Zurich | 24 |
| HAJ–ZRH | Hannover – Zurich | 24 |
| NCE–ZRH | Nice, Alpes-Maritimes – Zurich | 24 |
| BRU–ZRH | Zaventem – Zurich | 23 |
| BOD–ZRH | Bordeaux – Zurich | 22 |
| ORD–RFD | Chicago – Chicago/Rockford | 19 |
| BHX–ZRH | Birmingham, West Midlands – Zurich | 19 |
| BIQ–GVA | Biarritz – Geneva | 18 |
| VCE–ZRH | Venezia (VE) – Zurich | 18 |
| DRS–ZRH | Dresden – Zurich | 18 |
| GVA–ZRH | Geneva – Zurich | 18 |
| LUX–ZRH | Luxembourg – Zurich | 17 |
| DUS–ZRH | Düsseldorf – Zurich | 17 |
| KSC–ZRH | Košice – Zurich | 16 |
| CFU–GVA | Kerkyra (Corfu) – Geneva | 16 |
| POZ–ZRH | Poznań – Zurich | 16 |
| BRE–ZRH | Bremen – Zurich | 15 |
| GWT–ZRH | Sylt – Zurich | 14 |
| WRO–ZRH | Wrocław – Zurich | 14 |
| ARN–GVA | Stockholm – Geneva | 13 |
| GVA–LCA | Geneva – Larnaca | 12 |
| FLR–ZRH | Firenze (FI) – Zurich | 11 |
| CLJ–ZRH | Cluj-Napoca – Zurich | 10 |
| FRA–ZRH | Frankfurt am Main – Zurich | 9 |
| GDN–ZRH | Gdańsk – Zurich | 8 |
| GRZ–ZRH | Feldkirchen bei Graz – Zurich | 8 |
| GLA–ZRH | Glasgow – Zurich | 6 |
| SJJ–ZRH | Sarajevo – Zurich | 6 |
| BLQ–ZRH | Bologna – Zurich | 4 |
| STR–ZRH | Stuttgart – Zurich | 3 |
| CHR–ZRH | CHR – Zurich | 2 |
| TRS–VCEonce | Ronchi dei Legionari/Trieste – Venezia (VE) | 1 |
| GLA–SKPonce | Glasgow – Ilinden | 1 |
